Sterilization-in-Place (SIP) is the sterilization of suitable process equipment and pipework without dismantling them. A defined cycle, often using steam, exposes the relevant surfaces to validated conditions and records critical parameters such as temperature, pressure and time. SIP is distinct from Clean-in-Place (CIP): cleaning removes residues, while sterilization aims to inactivate microorganisms to the required level. The cycle and acceptance criteria depend on the equipment, product and applicable quality requirements.<\/p>\n\n\n
Related: CIP<\/a> \u00b7 GMP<\/a>.<\/p>","protected":false},"excerpt":{"rendered":" SIP sterilizes suitable process equipment in place using a defined, controlled cycle.<\/p>","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"wpai_generated_summary":"","footnotes":""},"categories":[32],"tags":[],"class_list":["post-38442","post","type-post","status-publish","format-standard","hentry","category-glossary"],"_links":{"self":[{"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/posts\/38442","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/comments?post=38442"}],"version-history":[{"count":0,"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/posts\/38442\/revisions"}],"wp:attachment":[{"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/media?parent=38442"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/categories?post=38442"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/accevo.com\/es\/wp-json\/wp\/v2\/tags?post=38442"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}