We combine compliance with production performance in one platform. Everything you expect from GMP-compliant software, connected to every machine on your floor and deployed in months.
A Manufacturing Execution System connects your enterprise systems to the shop floor and controls production in real time. MES systems in pharma have to do more: every batch runs under GMP, with traceability, audit trails and quality checks built into the workflow.
Accevo Pharma MES is built for that reality – batch processing, LIMS integration and real-time quality checks across drugs, vaccines, supplements and cosmetics. You make decisions on real production data and correlate it with utilities usage.
Release batches up to 35% faster with GMBR templates and review by exception.
Less validation work on your side – GMP, GAMP 5 and ALCOA+ ready, with platform validation included.
Go fully paperless – EBR, LIMS and QMS unified and synced in real time.
Connect any machine, legacy or new – through one vendor and our own in-house automation team.
We cover every stage of pharmaceutical production, from recipe management through dispensing, granulation, tablet manufacturing, packaging and palletizing.
Tablets produced and packed yearly per line
Ampoules and eye drops filled yearly
Tubes of creams and toothpaste filled yearly
Standards differ by industry, but the demand is the same: documented processes, traceable records and provable corrective action. An ISO 9001 QMS software foundation covers the core; industry layers add what your auditor asks for.
The core quality management standard: documented processes, quality policy and objectives, monitoring against those objectives, and continuous improvement. Accevo QMS maintains the records, audit trails and reports certification requires.
Automotive adds control plans, PPAP-grade evidence and rigorous SPC; medical devices (ISO 13485) add design and risk records with full device traceability. Both build on the same digital quality backbone.
For pharma and food, quality records must be ALCOA+ with electronic signatures and audit trails under FDA 21 CFR Part 11 – delivered together with Accevo EBR for batch-level compliance.
Instead of maintaining hundreds of MBR versions, you keep one Generic Master Batch Record (GMBR) for each family of similar products. Variable fields like dose strength, fill volume or packaging format sit on top of one approved workflow.
QA reviews only the deviations the system flags, then makes the disposition decision – release, reject or quarantine – on data pulled directly from PLCs and SCADA. Automated product disposition means every other parameter is validated against spec without manual checks.
One reusable template replaces hundreds of individual MBRs. Variable fields like dose strength, packaging format, and product specifications sit on top of a single approved workflow.
Every critical parameter (weight, temperature, pressure, dispensing accuracy) is checked against spec the moment it lands in the system, eliminating substance overdosing and protecting batch integrity downstream.
Our genealogy engine maps every batch back to raw materials and forward to shipped pallets. Production data captured for every batch includes component lots, operators, quantities, weights, changeover times, uptime, downtime, failures, speed loss and waste.
Accevo Pharma MES is built for that reality – batch processing, LIMS integration and real-time quality checks across drugs, vaccines, supplements and cosmetics. You make decisions on real production data and correlate it with utilities usage.
Start from a finished pallet and trace back to every raw material batch, equipment used and operator on shift. Or start from a suspect material and find every batch and shipment downstream.
Every action is logged with user, timestamp and reason. Records cannot be edited or deleted, only superseded with a new entry that preserves the original.
Every deviation gets a record, an owner and a CAPA workflow with timestamps. The full deviation lifecycle is documented and centralized in one place.
Shop floor digitization for pharmaceutical manufacturing starts here. Paper batch records, checklists and logbooks become digital steps that operators confirm as they work, with every entry timestamped and audit-ready.
MES software for pharmaceutical lab operations puts EBR, LIMS and QMS on one platform, so approved lab data feeds directly into the batch record in real time. Your QA team releases batches faster.
Your genealogy is automatically complete and auditable. Paperless manufacturing digitises every paper artifact on the floor: work orders, dispensing records, cleaning logs, deviation reports, quality control reports.
Accevo Pharma MES is developed under ISPE GAMP 5, so your own validation work is significantly reduced. The platform is ready for FDA 21 CFR Part 11 electronic records and signatures, EU GMP (EudraLex Volume 4), MHRA GMP, OMCL PA/PH/OMCL and WHO Data Integrity guidelines.
Every action is captured under ALCOA+ principles: attributable, legible, contemporaneous, original, accurate, complete, consistent, enduring and available. Audit trail, electronic batch records, deviation management and validation documentation come with the platform.
Supported by CenterLine parameter tracking and structured defect handling workflows.
Manufacturing in the region for the region, next to our customers is a pillar of our operations strategy. We invested massively in our factories over the last years to increase capacity.
Completing these investments with the best digitalization solution of all manufacturing systems is a key part of our program toward more efficiency and agility. In a great collaboration with Accevo, we are rolling out our plans.
Veronica Ottonello
Industrial Process Engineer, Bormioli Pharma
First Value Live
Real-time orchestration of orders, recipes, deviations and signatures.
From weighing and dispensing to room readiness, we orchestrate the operator’s shift. Digital SOPs replace paper instructions. Container management tracks every intermediate product. Room status is verified before the operator enters. Whoever runs the line, the batch runs the same way.
Operator Guidance & Digital SOPs
Every paper form on your shop floor (work orders, dispensing records, cleaning logs, deviation reports) becomes a digital form in Accevo. Operators sign electronically. Records land in the batch record automatically.
Weighing & Dispensing
Direct integration with scales and dispensing equipment. The system verifies material identity, weighs against the target, captures the operator’s signature, and writes the entry to the EBR automatically.
Container Management
Every intermediate container has a digital identity. The system tracks where it is, what is in it, when it was last cleaned, and whether it is released for the next step.
Rooms Management
Before an operator enters a room, the system verifies it is clean, qualified, and free of the previous product. Changeover checklists are signed digitally. Cross-contamination risks are flagged in real time.
Digitalization in pharma is not a choice, it is the only way forward. I believe with our knowledge and commitment and IT expertise from Accevo we will create a good MES that will make our dose easier and increase our efficiency.
Maja Lazarova
Head of production, Alkaloid AD Skopje
Run at full speed time increas
Micro stops time reduction
Batch release time reduction
Setup time reduction
Over 25 000 process and discrete manufacturing machines connected globally.
Our systems support production environments in 38 countries worldwide.
More than two decades of experience delivering MES/MOM software for global manufacturers.
Machine connectivity and real-time OEE monitoring across Bormioli’s largest Italian facility.
Electronic Batch Records and machine connectivity delivering 15% productivity increase and reduced batch control errors.
Piotr Kańka, Industrial Software Expert
MES stands for Manufacturing Execution System. In pharma, an MES runs and documents production in real time under GMP - electronic batch records, genealogy, deviations and quality checks in one workflow. Accevo Pharma MES connects it to every machine on the floor and to your ERP, LIMS and QMS.
The MES system is a modern software which allows to completely manage the production process. It enables work planning, continuous monitoring of performed actions, efficient execution and optimisation of activities.
What are the main benefits of using MES in pharma? First of all, constant communication with all equipment responsible for production. Accevo PHARMA Suite controls the parameters of ingredients in real time, eliminating the possibility of substance overdosing.
For GMP batch manufacturing and data integrity, choose an MES built under ISPE GAMP 5 that pulls data straight from PLCs and SCADA - so records are contemporaneous and attributable by design, not typed in by hand. Accevo Pharma MES is ready for FDA 21 CFR Part 11, EU GMP (EudraLex Vol. 4), MHRA GMP and WHO data integrity guidelines, with every action captured under ALCOA+.
The system validates every critical parameter against spec as data lands from PLCs and SCADA, and flags only deviations. QA reviews the exceptions and records the disposition - release, reject or quarantine - against a complete, ALCOA+ audit trail.
Accevo Pharma MES is a Manufacturing Execution System for pharmaceutical manufacturing - tablets, syrups, creams, injectables and liquids. MES systems in pharma keep every batch under GMP and connect the shop floor to your ERP, LIMS and QMS. You run any product on one approved, validated workflow.
What opportunities does the Manufacturing Execution System for pharma industries provide? First of all, it provides safety. MES systems in pharma enable real-time monitoring of the batches produced. If it turns out that a substance that is part of a drug has been stored incorrectly, the manufacturer can react immediately and stop the production of a specific batch and not all the components moving along the production line.
It’s no secret that every step of the pharmaceutical manufacturing process must be documented. However, managing paper documentation can be extremely time-consuming for pharmaceutical manufacturers, and human error can be relatively common. For this reason, pharmaceutical companies decided to implement what is known as Electronic Batch Record (EBR) in order
Production optimization and related analytics is important for all businesses, regardless of industry. However, there are companies with special characteristics. This group includes, among others, the pharma cosmetics sector characterized by various forms of cosmetics and a large amount of raw materials used in production. In order to avoid overproduction
Digitalization has firmly established itself in everyday production processes, regardless of the industry. Nevertheless, habits remain from the days before widespread digitalization, traditional solutions not going hand in hand with business efficiency. Paper is an example of this – it is still common when creating documentation used on the shop
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